Charlie Harper (Charlie Sheen, “Spin City”) é um solteirão bem de vida que vive numa casa na praia, tem um belo carro na garagem e tem uma grande facilidade de conquistar as mulheres. Seu estilo de vida casual em Malibu é interrompido quando seu irmãoo Alan (Jon Cryer), que está no meio de um divórcio, e seu sobrinho de 10 anos Jake (Angus T. Jones), chegam para morar com ele. Melanie Lynskey, Conchata Ferrell, Charlie Sheen, Angus T. Jones, Holland Taylor, Jon Cryer e Marin Hinkle Para complicar ainda mais as coisas, há também a obcecada e controladora mãe de Charlie e Alan, Evelyn (Holland Taylor); a afastada mulher de Alan, Judith (Marin Hinkle, “Once and Again”), que “acredita” que é gay; e a atraente e meio estranha vizinha Rose (Melanie Lynskey), que teve um breve romance com Charlie e estão determinada a estar presente na vida dele custe o que custar.Apesar desse estranho relacionamento, Charlie e Alan descobrem que ambos tem uma coisa em comum: eles amam Jake e querem o melhor para ele. Os irmãos concordam em criar um lar adequado para Jake na casa de Charlie, e juntos esses dois homens e meio encaram os desafios de (em alguns casos, finalmente) se tornarem adultos.
1ª temporada
1×01 – Pilot
1×02 – Big Flappy Bastards
1×03 – Go East on Sunset Until You Reach the Gates of Hell
1×04 – If I Can’t Write My Chocolate Song I’m Going to Take a Nap
1×05 – The Last Thing You Want Is to Wind Up With a Hump
1×06 – Did You Check With The Captain Of The Flying Monkeys
1×07 – If They Do Go Either Way, They’re Usually Fake
1×08 – Twenty-Five Little Pre-pubers Without A Snoot-ful
1×09 – Phase One Complete
1×10 – Merry Thanksgiving
1×11 – Alan Harper,Frontier Chiropractor
1×12 – Camel filters + pheromones
1×13 – Sara Like Puny Alan
1×14 – I Can’t afford Hyenas
1×15 – Round One To The Hot Crazy Chick
1×16 – That Was Saliva, Alan
1×17 – Ate the Hamburguers Wearing Hats
1×18 – An Old Flame With A New Wick
1×19 – I Remember The Coatroom I Just don’t Remember You
1×20 – Hey I Can Pee Outside In The Dark
1×21 – No Sniffing, No Wowing
1×22 – My Doctor Has a Cow Puppet
1×23 – Just Like Buffalo
1×24 – Can You Feel My Finger (Season Finale)
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2ª temporada
2×01 – Back Off, Mary Poppins
2×02 – Enjoy Those garlic Balls
2×03 – A Bag Full Of Jawea
2×04 – Go, Get Mommy
2×05 – Bad News From Clinic
2×06 – The Price of Health Gums is Eternal Vigilance
2×07 – A Kosher Slaughterhouse Out in Fontana
2×08 – Frankenstein and the Horny Villages
2×09 – Yes, Monsignor!
2×10 – Salmon Under My Sweater
2×11 – Last Chance to See Those Tatoos
2×12 – A Lungful of Alan
2×13 – Get Off My Hair
2×14 – Those Big Pink Things with Coconut
2×15 – Smell the Umbrella Stand
2×16 – Can you Eat Human Flesh with Wooden Teeth?
2×17 – Woo-Hoo, A Hernia-Exam!
2×18 – It Was Mame, Mom
2×19 – A Low, Gutteral Tongue-Flapping Noise
2×20 – I Always Wanted a Shaved Monkey
2×21 – A Sympathetic Crotch to Cry On
2×22 – That Old Hose Bag Is My Mother
2×23 – Squab, Squab, Squab, Squab, Squab
2×24 – Does This Smell Funny to You? (Season Finale)
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3ª temporada
3×01 – Weekend in Bangkok with Two Olympic Gymnasts
3×02 – Principal Gallagher’s Lesbian Lover
3×03 – Carpet Burns and a Bite Mark
3×04 – Your Dismissive Attitude Toward Boobs
3×05 – We Called it Mr. Pinky!
3×06 – Hi, Mr. Horned One!
3×07 – Sleep Tigh, Puddin’ Pop
3×08 – That Voodoo That I Do
3×09 – Madame and Her Special Friend
3×10 – Something Salted and Twisted
3×11 – Santa’s Village of the Damned
3×12 – That Special Tug
3×13 – Humiliation is a Visual Medium
3×14 – Love Isn’t Blind, It’s Retarded
3×15 – My Tongue is Meat
3×16 – Ergo The Booty Call
3×17 – The Unfortunate Little Schnauser
3×18 – The Spit-Covered Cobbler
3×19 – Golly Moses, She’s A Muffin
3×20 – Always a Bridesmaid, Never a Burro
3×21 – And the Plot Moistens
3×22 – Just Once With Aunt Sophie
3×23 – Arguments for the Quickie
3×24 – That Pistol-Packin’ Hermaphrodite (Season Finale)
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4ª Temporada
4×01 – Working for Caligula
4×02 – Who’s Vod Kanockers
4×03 – The Sea is a Harsh Mistress
4×04 – A Pot Smoking Monkey
4×05 – A Live Women of Proven Fertility
4×06 – Apologies for the Frivolity
4×07 – Repeated Blows to his Unformed Head
4×08 – Release the Dogs
4×09 – Corey Been Dead For an Hour
4×10 – Kissing Abraham Lincoln
4×11 – Walnuts and Demerol
4×12 – Castrating Sheep in Montana
4×13 – Don’t Worry, Speed Racer!
4×14 – That’s Summer Sausage, Not Salami
4×15 – My Damn Stalker ->
4×16 – Young People Have Phlegm Too
4×17 – I Merely Slept With a Commie
4×18 – It Never Rains in Hooterville
4×19 – Smooth as a Ken Doll
4×20 – Aunt Myra Doesn’t Pee a Lot
4×21 – Tucked, Taped and Gorgeous
4×22 – Mr. McGlue’s Feedbag
4×23 – Anteaters. They´re Just Crazy-lookin
4×24 – Prostitutes and Gelato (Season Finale)
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5ª Temporada
5×01 – Large Birds, Spiders and Mom
5×02 – Media Room Slash Dungeon
5×03 – Dum Diddy Dum Diddy Doo
5×04 – City of Great Racks
5×05 – Putting Swim Fins on a Cat
5×06 – Help Daddy Find His Toenail
5×07 – The Leather Gear is in the Guest Room
5×08 – Is There a Mrs. Waffles?
5×09 – Shoes, Hats, Pickle, Jar Lids.
5×10 – Kinda Like Necrophilia
5×11 – Meander To Your Dander
5×12 – A Little Clammy and None Too Fresh
5×13 – The Soil is Moist
5×14 – Winky-Dink Time
5×15 – Rough Night in Hump Junction
5×16 – Look at Me, Mommy, I´m Prett
5×17 – Fish In A Drawer
5×18 – If My Hole Could Talk
5×19 – Waiting for the Right Snapper (Season Finale)
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6ª Temporada
6×01 – Taterhead Is Our Love Child?
6×02 – Pie Hole, Herb
6×03 – Damn You, Eggs Benedict
6×04 – The Flavin’ and the Mavin’
6×05 – A Jock Strap in Hell
6×06 – It’s Always Nazi Week
6×07 – Best Ho Money Can Buy
6×08 – Pinocchio’s Mouth
6×09 – The Mooch At The Boo
6×10 - He Smelled The Ham He Got Excited
6×11 - The Devil’s Lube
6×12 - Thank God for Scoliosis
6×13 – I Think You Offended Don
6×14 - David Copp
6×15 - I’d Like The Cat First
6×16 – She’ll Still Be Dead At Halftime
6×17 - The ‘Ocu’ Or The ‘Pado’?
6×18 – My Son’s Enormous Head
6×19 – The Two Finger Rule
6×20 - Hello, I am Alan Cousteau
6×21 - Above Exalted Cyclops
6×22 - Sir Lancelot’s Littler Box
6×23 - Good Morning, Mrs. Butterworth
6×24 - Baseball Better with Steroids ( Season Finale )
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7ª Temporada
7×01 – 818-jklpuzo
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7×02 – Whipped Unto the Third Generation
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7×03 – Mmm, fish. Yum.
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7×04 – Laxative Tester, Horse Inseminator
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7×05 – For the Sake of the Child
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7×06 – Give Me Your Thumb
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7×07 – Untainted by Filth
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